MANTA
MANTA

MANTA


Multiscale Analysis for N-dimensional Transcriptome Alignment

TODOs
Working Conda env with all necessary packages
Fast way to create multi-scale voxels
Binning of transcriptome data into voxels (FAST)
  • The goal is to do this really fast. This should absolutely not take more than a few seconds.
Voxelization pipeline (already in package format!)
Voxel representation of transcriptome data (i.e. allow for custom or built-in method to collect and voxel features in a modular format)
Find/discuss potential spatial embedding methods
  • STAMP - Topic Modeling, potentially VERY interesting! →
Figure out rigid alignment of voxel representations
  • Generalized Procrustes Analysis
  • Affine transform (scikit-learn)
Mathematical derivation of all necessary models
  • What types of models!